The Journal of general virology · 2016
Biosafety standards for working with Crimean-Congo hemorrhagic fever virus.
СтатьяНазвание и аннотация: Перевод в очереди
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Weidmann Manfred, Avsic-Zupanc Tatjana, Bino Silvia, Bouloy Michelle, Burt Felicity, Chinikar Sadegh, Christova Iva, Dedushaj Isuf, El-Sanousi Ahmed, Elaldi Nazif, Hewson Roger, Hufert Frank T, Humolli Isme, Jansen van Vuren Petrus, Koçak Tufan Zeliha, Korukluoglu Gülay, Lyssen Pieter, Mirazimi Ali, Neyts Johan, Niedrig Matthias, Ozkul Aykut, Papa Anna, Paweska Janusz, Sall Amadou A, Schmaljohn Connie S, Swanepoel Robert, Uyar Yavuz, Weber Friedemann, Zeller Herve
Аннотация
In countries from which Crimean-Congo haemorrhagic fever (CCHF) is absent, the causative virus, CCHF virus (CCHFV), is classified as a hazard group 4 agent and handled in containment level (CL)-4. In contrast, most endemic countries out of necessity have had to perform diagnostic tests under biosafety level (BSL)-2 or -3 conditions. In particular, Turkey and several of the Balkan countries have safely processed more than 100 000 samples over many years in BSL-2 laboratories. It is therefore advocated that biosafety requirements for CCHF diagnostic procedures should be revised, to allow the tests required to be performed under enhanced BSL-2 conditions with appropriate biosafety laboratory equipment and personal protective equipment used according to standardized protocols in the countries affected. Downgrading of CCHFV research work from CL-4, BSL-4 to CL-3, BSL-3 should also be considered.