Drug and alcohol dependence · 2015
Serum level of vascular endothelial growth factor decreased in chronic ketamine abusers.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Fan Ni, Zhang Minling, Xu Ke, Ke Xiaoyin, Ding Yi, Wang Daping, Liu Yuping, Ning Yuping, Deng Xuefeng, He Hongbo
Аннотация
AIMS: To evaluate the serum level of vascular endothelial growth factor (VEGF) in a group of chronic ketamine abusers in comparison to healthy controls.
METHODS: Eighty-one ketamine abusers who were hospitalized for the treatment of ketamine dependence and 39 healthy controls were recruited. Serum VEGF level was measured by enzyme linked immunosorbent assay (ELISA). Psychopathological symptoms were assessed using Positive and Negative Syndrome Scale (PANSS), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI).
RESULTS: Serum level of VEGF was significantly lower in chronic ketamine abusers compared to healthy controls (64.6±42.1 vs. 92.4±59.4pg/ml, F=7.243, p=0.008).
CONCLUSIONS: Serum level of VEGF decreased in chronic ketamine abusers compared to healthy controls.
METHODS: Eighty-one ketamine abusers who were hospitalized for the treatment of ketamine dependence and 39 healthy controls were recruited. Serum VEGF level was measured by enzyme linked immunosorbent assay (ELISA). Psychopathological symptoms were assessed using Positive and Negative Syndrome Scale (PANSS), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI).
RESULTS: Serum level of VEGF was significantly lower in chronic ketamine abusers compared to healthy controls (64.6±42.1 vs. 92.4±59.4pg/ml, F=7.243, p=0.008).
CONCLUSIONS: Serum level of VEGF decreased in chronic ketamine abusers compared to healthy controls.