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DOI 10.2196/84657

Медицинская библиотека · JMIR aging · 2026

Demoralization and Mental Disorders in Community-Dwelling Older Adults: Cluster Analysis.

Onofrio Alice, Ferrara Maria, Domenicano Ilaria, Belvederi Murri Martino, Toffanin Tommaso, Nanni Maria Giulia, Canuto Alessandra, Weber Kerstin, Volkert Jana, Schulz Holger, Härter Martin, Andreas Sylke, Grassi Luigi

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Аннотация

BACKGROUND

Demoralization negatively affects the quality of life, especially in people with mental disorders.

OBJECTIVE

This study aims to assess demoralization in a cohort of community-dwelling older adults, to identify groups of individuals who share similar characteristics in terms of mental health conditions and the severity of demoralization domains, and to investigate the different characteristics across these groups.

METHODS

Participants were enrolled in 3 centers as part of the cross-sectional MentDis_ICF65+ study and were assessed using the Demoralization Scale and the Composite International Diagnostic Interview at baseline. A cluster analysis was conducted using the partitioning around medoids algorithm with Gower's distance to classify individuals based on demoralization severity and the diagnosis of mental health disorders, allocating individuals to a distinct number of patterns by examining their similarities across these variables.

RESULTS

Among the final sample of 1369 participants, 3 clusters were identified: the "low psychopathology" cluster, with very few mental health diagnoses; the "affective" cluster, characterized by affective disorders (100% of participants); and the "anxiety" cluster, characterized by anxiety disorders (100% of participants). Men were prevalent in the "low psychopathology" cluster (n=635, 59.1%; P<.001), while women were more prevalent in the "affective" cluster (n=133, 72.3%; P<.001) and the "anxiety" cluster (n=79, 71.8%; P<.001). The "affective" cluster had the highest mean scores for disheartenment (17.1, SD 6.7; P<.001), dysphoria (12.1, SD 3.5; P<.001), and loss of meaning (11.8, SD 4.9; P<.001) but the lowest for sense of failure (17.4, SD 3.2; P<.001).

CONCLUSIONS

The identification of different clusters of demoralization and mental health disorders in community-dwelling older adults, as well as sex-based differences, highlights the need for tailored mental health interventions in this vulnerable population.

Для цитирования: Onofrio Alice, Ferrara Maria, Domenicano Ilaria, Belvederi Murri Martino, Toffanin Tommaso, Nanni Maria Giulia, Canuto Alessandra, Weber Kerstin, Volkert Jana, Schulz Holger, Härter Martin, Andreas Sylke, Grassi Luigi. Demoralization and Mental Disorders in Community-Dwelling Older Adults: Cluster Analysis.. JMIR aging. 2026. DOI: 10.2196/84657.

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