VibroIntegração BioMolecular: a structured multimodal protocol for autonomic regulation in community healthcare.

VibroIntegração BioMolecular® (VIB) is a structured, low-cost multimodal protocol designed to support autonomic regulation in community healthcare settings. Organized into four sequential stages-guided muscle relaxation, resonance frequency breathing, multisensory interoceptive integration, and psychoeducation in a regulated state-the protocol aims to facilitate cardiorespiratory synchronization and self-regulation skills. This descriptive case series describes the implementation of VIB in primary care and community-based programs in southern Brazil (n = 38; 21 in primary care and 17 in palliative care settings). Physiological monitoring included heart rate variability (HRV)-based coherence monitoring, heart rate trends, respiratory rate, and subjective markers assessed longitudinally across sessions. Representative intra-individual changes included an increase in high-coherence from 0 to 53% and a reduction in low-coherence from 80 to 16% in a cardiovascular case. Similar directional patterns were observed across the four monitored cases. No adverse events were recorded, and the protocol was implemented without modification of prescribed medical treatments. While the study design does not allow causal inference, the findings suggest that the structured sequential organization of relaxation and resonance breathing may facilitate short-term autonomic modulation in real-world community environments. These preliminary results support the feasibility, safety, and reproducibility of the VIB protocol and provide a foundation for future controlled investigations.