Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons · 2026
Multimodal diagnosis of periprosthetic joint infection after total ankle arthroplasty.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Pfahl Kathrin, Eder Julia, Krenn Veit, Faust Leon Marcel, Zhang Yunjie, Boecker Wolfgang, Holzapfel Boris M, Walther Markus
Аннотация
BACKGROUND: Diagnosing periprosthetic joint infection (PJI) after total ankle arthroplasty (TAA) remains challenging. This study evaluated clinical, laboratory, imaging, microbiological and histopathological parameters in suspected PJI after TAA. We hypothesized that a multimodal approach improves diagnosis.
METHODS: This retrospective study included 57 patients with suspected PJI after TAA and applied European Bone and Joint Infection Society (EBJIS) criteria. Pre- and intraoperative parameters were analyzed using correlation, group comparison and L1-regularized logistic regression.
RESULTS: 33 patients were classified as infection unlikely, 5 as likely, and 19 as confirmed. Strong associations with PJI were observed for 99mTc-SPECT/CT (rs = 0.88), synovial neutrophil percentage, blood culture positivity, microbiology, histology, and sonication (all p < .001).
CONCLUSIONS: Clinical signs, synovial fluid analysis, microbiology, histology, sonication, and 99mTc-SPECT/CT showed substantial discriminatory value and support a multimodal diagnostic strategy in suspected ankle PJI.
LEVELS OF EVIDENCE: Level IV.
METHODS: This retrospective study included 57 patients with suspected PJI after TAA and applied European Bone and Joint Infection Society (EBJIS) criteria. Pre- and intraoperative parameters were analyzed using correlation, group comparison and L1-regularized logistic regression.
RESULTS: 33 patients were classified as infection unlikely, 5 as likely, and 19 as confirmed. Strong associations with PJI were observed for 99mTc-SPECT/CT (rs = 0.88), synovial neutrophil percentage, blood culture positivity, microbiology, histology, and sonication (all p < .001).
CONCLUSIONS: Clinical signs, synovial fluid analysis, microbiology, histology, sonication, and 99mTc-SPECT/CT showed substantial discriminatory value and support a multimodal diagnostic strategy in suspected ankle PJI.
LEVELS OF EVIDENCE: Level IV.