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Addictive behaviors · 2026

The interactive role of perceived stress and nicotine dependence on failure to maintain abstinence after a smoking cessation treatment: a sex-stratified survival analysis.

СтатьяНазвание и аннотация: Перевод в очереди
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Ramos-Carro María, Martínez-Vispo Carmela, López-Durán Ana, Becoña Elisardo

Аннотация

INTRODUCTION: Maintaining abstinence after smoking cessation is challenging, and factors associated with cessation success may differ by sex. Given the relevance of nicotine dependence and perceived stress in cessation outcomes, this study aimed to examine, separately for males and females, whether the interaction between perceived stress and nicotine dependence predicts failure to maintain abstinence over the year following a cognitive-behavioral smoking-cessation intervention.

METHODS: The sample comprised 440 adults (64.3% female, Mage = 45.19) who quit smoking after receiving a smoking cessation intervention between 2015 and 2022. Study variables (perceived stress and nicotine dependence) were assessed at pretreatment. Failure to maintain abstinence was defined as smoking for at least seven consecutive days since the end of the smoking cessation intervention. Hierarchical Cox proportional-hazards regression models were conducted, separately in males and females, to analyze the association of nicotine dependence and perceived stress and their interaction with risk of failure to maintain abstinence.

RESULTS: The interaction between perceived stress and nicotine dependence was significant in males (HR = 2.23, 95% CI [1.37, 3.62], p = 0.001), but not in females. Perceived stress significantly predicted risk of failure to maintain abstinence in males with low nicotine dependence (HR = 1.36, 95% CI [1.01, 1.83], p = 0.044), but not in males with high nicotine dependence.

CONCLUSIONS: These findings identify perceived stress as a potential intervention target for preventing failure to maintain abstinence among males with low nicotine dependence. These results reinforce the relevance of incorporating sex- and nicotine-dependence-specific strategies in smoking cessation interventions.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты