Psychiatry research · 2026
Effect of dialectical behavior therapy on affective symptoms in borderline personality disorder: A systematic review and meta-analysis.
СтатьяСистематический обзорМетаанализНазвание и аннотация: Перевод в очереди
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Li Yaling, Mao Weixia
Аннотация
BACKGROUND: Dialectical Behavior Therapy (DBT), originally designed for emotional dysregulation in borderline personality disorder (BPD), has shown effective overall, but its specific effect on depression and anger expression stays underexplored.
OBJECTIVES: This study systematically reviews and meta-analyzes controlled trials analyzing the impact of standard DBT on post-treatment depression and anger expression among adults having BPD.
METHODS: This study performed by searching PubMed, Scopus, and Web of Science through February 24, 2025, for randomized and high-quality non-randomized trials. Eligible studies reported validated, quantitative post-treatment measures of depression or anger expression. Random-effects meta-analyses assessed Cohen's d for depression and anger; Knapp-Hartung adjustments were applied to the anger analysis. Heterogeneity was calculated, and meta-regression tested intervention duration and publication year as moderators for depression.
RESULTS: From 648 records, seven trials met inclusion criteria, spanning 8 weeks to 12 months across outpatient and community settings. DBT presented a moderate statically significant reduction in depression with SMD of -0.59 (95% CI -1.02 to -0.16; p = 0.007; I² = 80.5%). DBT also presented a moderate statically significant reduction in anger expression with SMD of -0.738 (95% CI -1.371 to -0.104, p = 0.023, I² = 83.3%; and 95% -1.779 to 0.304, p = 0.110 with Knapp-Hartung). High heterogeneity and limited trial numbers constrained statistical power.
CONCLUSIONS: Standard DBT demonstrated moderate, directionally consistent improvements in depressive symptoms and anger expression in adults with BPD, supporting its emotion-regulation framework. Larger, multi-site RCTs with standardized outcomes and long-term follow-up are needed to confirm these effects and identify key moderators.
OBJECTIVES: This study systematically reviews and meta-analyzes controlled trials analyzing the impact of standard DBT on post-treatment depression and anger expression among adults having BPD.
METHODS: This study performed by searching PubMed, Scopus, and Web of Science through February 24, 2025, for randomized and high-quality non-randomized trials. Eligible studies reported validated, quantitative post-treatment measures of depression or anger expression. Random-effects meta-analyses assessed Cohen's d for depression and anger; Knapp-Hartung adjustments were applied to the anger analysis. Heterogeneity was calculated, and meta-regression tested intervention duration and publication year as moderators for depression.
RESULTS: From 648 records, seven trials met inclusion criteria, spanning 8 weeks to 12 months across outpatient and community settings. DBT presented a moderate statically significant reduction in depression with SMD of -0.59 (95% CI -1.02 to -0.16; p = 0.007; I² = 80.5%). DBT also presented a moderate statically significant reduction in anger expression with SMD of -0.738 (95% CI -1.371 to -0.104, p = 0.023, I² = 83.3%; and 95% -1.779 to 0.304, p = 0.110 with Knapp-Hartung). High heterogeneity and limited trial numbers constrained statistical power.
CONCLUSIONS: Standard DBT demonstrated moderate, directionally consistent improvements in depressive symptoms and anger expression in adults with BPD, supporting its emotion-regulation framework. Larger, multi-site RCTs with standardized outcomes and long-term follow-up are needed to confirm these effects and identify key moderators.