JCPP advances · 2025
Mapping developmental transitions in mental health from mid- to late-adolescence: Concurrent and longitudinal links to cognition.
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Mareva Silvana, Parker Jenna, Bennett Marc, Pass Laura, Banaschewski Tobias, Bokde Arun L W, Desrivières Sylvane, Flor Herta, Hohmann Sarah, Orfanos Dimitri Papadopoulos, Garavan Hugh, Gowland Penny, Walter Henrik, Brühl Rüdiger, Martinot Jean-Luc, Paillère Martinot Marie-Laure, Artiges Eric, Nees Frauke, Paus Tomáš, Poustka Luise, Smolka Michael N, Vaidya Nilakshi, Whelan Robert, Schumann Gunter, Holmes Joni
Аннотация
BACKGROUND: Developmental changes in mental health are mostly mapped between childhood and adolescence or childhood and adulthood. This study maps developmental transitions in mental health profiles from mid- to late-adolescence, exploring how these transitions relate to cognitive function in mid-adolescence.
METHOD: Participants from the IMAGEN cohort (N = 1304) were followed from mid- (14 years) to late (22 years) adolescence. K-means clustering was applied to data from those with elevated mental health problems to identify common profiles of mental health symptoms at each timepoint (n = 784 at 14 years, n = 655 at 22 years). Those with no mental health symptoms formed a comparison group (n = 520 at 14 years, n = 649 at 22 years). Transitions between the groups were mapped across time and related to cognitive function at age 14.
RESULTS: Three distinct mental health profiles were identified: presentations of externalising, internalising, or social problems. These were similar in mid- and late adolescence. Externalising problems were more common in mid-adolescence. Persistent externalising and social problems were related to cognitive function in mid-adolescence, but problems that emerged or resolved in late adolescence were not.
CONCLUSIONS: These data highlight the importance of understanding the developmental context in which mental health symptoms occur, and the cognitive factors linked to their persistence.
METHOD: Participants from the IMAGEN cohort (N = 1304) were followed from mid- (14 years) to late (22 years) adolescence. K-means clustering was applied to data from those with elevated mental health problems to identify common profiles of mental health symptoms at each timepoint (n = 784 at 14 years, n = 655 at 22 years). Those with no mental health symptoms formed a comparison group (n = 520 at 14 years, n = 649 at 22 years). Transitions between the groups were mapped across time and related to cognitive function at age 14.
RESULTS: Three distinct mental health profiles were identified: presentations of externalising, internalising, or social problems. These were similar in mid- and late adolescence. Externalising problems were more common in mid-adolescence. Persistent externalising and social problems were related to cognitive function in mid-adolescence, but problems that emerged or resolved in late adolescence were not.
CONCLUSIONS: These data highlight the importance of understanding the developmental context in which mental health symptoms occur, and the cognitive factors linked to their persistence.