Der Nervenarzt · 2026
[The new S3 guideline on schizophrenia (living) 2025].
Аннотация на английскомСтатьяОбзорНазвание и аннотация: Перевод в очереди
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Halms Theresa, Gaebel Wolfgang, Leucht Stefan, Falkai Peter, Lincoln Tania, Bechdolf Andreas, Correll Christoph U, Schmidt Stefanie J, Lambert Martin, Wobrock Thomas, Hasan Alkomiet
Аннотация
BACKGROUND: On 15 October 2025, the revised S3 guideline on schizophrenia (living) was published and transferred to the MAGICapp evidence ecosystem and will be updated annually in the future.
OBJECTIVE: This narrative review summarizes essential innovations and explains their development.
MATERIAL AND METHODS: New and revised recommendations and MAGICapp background information were extracted and summarized.
RESULTS AND CONCLUSION: The guideline is now fully integrated into MAGICapp and annually updated. Key changes include a downgrading of the recommendation for antipsychotic monotherapy, a substantial expansion of guidance on adverse effect monitoring and management and a strengthened emphasis on evidence-based psychotherapeutic interventions, such as metacognitive training and systemic therapy. Additionally, 4 new recommendations (digital/technology-assisted interventions, mindfulness-based procedures, acceptance and commitment therapy [ACT], trauma-focussed therapy for post-traumatic stress disorder [PTSD]) were implemented and 12 were removed. All chapters were comprehensively revised.
OBJECTIVE: This narrative review summarizes essential innovations and explains their development.
MATERIAL AND METHODS: New and revised recommendations and MAGICapp background information were extracted and summarized.
RESULTS AND CONCLUSION: The guideline is now fully integrated into MAGICapp and annually updated. Key changes include a downgrading of the recommendation for antipsychotic monotherapy, a substantial expansion of guidance on adverse effect monitoring and management and a strengthened emphasis on evidence-based psychotherapeutic interventions, such as metacognitive training and systemic therapy. Additionally, 4 new recommendations (digital/technology-assisted interventions, mindfulness-based procedures, acceptance and commitment therapy [ACT], trauma-focussed therapy for post-traumatic stress disorder [PTSD]) were implemented and 12 were removed. All chapters were comprehensively revised.