Journal of medical microbiology · 2010
Multilocus variable-number tandem repeat analysis of Vibrio cholerae O1 El Tor strains harbouring classical toxin B.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Choi Seon Young, Lee Je Hee, Jeon Yoon-Seong, Lee Hye Ri, Kim Eun Jin, Ansaruzzaman M, Bhuiyan Nurul A, Endtz Hubert P, Niyogi S K, Sarkar B L, Nair G Balakrish, Nguyen Binh Minh, Hien Nguyen Tran, Czerkinsky Cecil, Clemens John D, Chun Jongsik, Kim Dong Wook
Аннотация
Atypical Vibrio cholerae O1 strains - hybrid strains (strains that cannot be classified either as El Tor or classical biotype) and altered strains (El Tor biotype strains that produce classical cholera toxin) - are currently prevalent in Asia and Africa. A total of 74 hybrid and altered strains that harboured classical cholera toxin were investigated by multilocus variable-number tandem repeat analysis (MLVA). The results showed that the hybrid/altered strains could be categorized into three groups and that they were distant from the El Tor strain responsible for the seventh cholera pandemic. Hybrid/altered strains with a tandem repeat of the classical CTX prophage on the small chromosome were divided into two MLVA groups (group I: Mozambique/Bangladesh group; group III: Vietnam group), and altered strains with the RS1-CTX prophage containing the El Tor type rstR and classical ctxB on the large chromosome were placed in two MLVA groups (group II: India/Bangladesh group; group III: India/Vietnam group).