Innovative Three-dimensional-printed Appliance for the Management of Neuropathologic Chewing in a Child.

Neuropathologic chewing is an involuntary chewing reflex characterized by repetitive, forceful jaw movements, often leading to self-inflicted oral trauma. This case report aims to describe the dental management of a 13-year-old male with GNAO1-associated disorder presenting with severe neuropathologic chewing and resulting oral trauma. A novel, custom-designed three-dimensional (3D)-printed intraoral appliance was fabricated to protect the oral tissues. The appliance prevented further self-inflicted injury and supported tissue healing, significantly improving the patient's quality of life. This case highlights the role of personalized dental intervention in managing neuropathologic chewing. It emphasizes the potential of 3D printing as an innovative and effective solution for complex neurogenetic disorders and underscores the importance of interdisciplinary care in pediatric dental management.