Current issues in molecular biology · 2019
Mobile Genetic Elements in Streptococci.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Lu Miao, Gong Tao, Zhang Anqi, Tang Boyu, Chen Jiamin, Zhang Zhong, Li Yuqing, Zhou Xuedong
Аннотация
Streptococci are a group of Gram-positive bacteria belonging to the family Streptococcaceae, which are responsible of multiple diseases. Some of these species can cause invasive infection that may result in life-threatening illness. Moreover, antibiotic-resistant bacteria are considerably increasing, thus imposing a global consideration. One of the main causes of this resistance is the horizontal gene transfer (HGT), associated to gene transfer agents including transposons, integrons, plasmids and bacteriophages. These agents, which are called mobile genetic elements (MGEs), encode proteins able to mediate DNA movements. This review briefly describes MGEs in streptococci, focusing on their structure and properties related to HGT and antibiotic resistance.
Предметные рубрики MeSH
Anti-Bacterial AgentsBacterial ProteinsConjugation, GeneticDrug Resistance, Multiple, BacterialGene Expression Regulation, BacterialGene Transfer, HorizontalGenome, BacterialHost-Pathogen InteractionsHumansInterspersed Repetitive SequencesStreptococcal InfectionsStreptococcus pneumoniaeStreptococcus pyogenesTransformation, BacterialVirulence