Anticancer research · 1998
The efficacy of hyperthermia combined with radiation therapy for high-grade soft tissue sarcoma.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Nakano H, Higaki S, Tateishi A
Аннотация
BACKGROUND: We have investigated the efficacy of preoperative hyperthermia combined with radiation therapy (HIRP) in cases of soft tissue sarcoma (STS) that could be consequently treated with limb salvage.
MATERIALS AND METHODS: Thirteen patients with STS in an extremity received HIRP at our institution. Local hyperthermia for 1 hour was administered eight to ten times. Radiation therapy (40-60 Gy) was administered at 2 Gy per session. The operation was performed at 2 or 3 weeks after HIRP.
RESULTS: Limb salvage surgery was achieved in 12 patients. No local recurrence was observed during a mean follow-up of 27 months. 7 patients had shown only a partial response to the HIRP. There was no correlation between the histological response and the observed reduction in tumor volume.
CONCLUSIONS: The results of this study suggested that HIRP was an effective local treatment for limb salvage in limb-threatening STS.
MATERIALS AND METHODS: Thirteen patients with STS in an extremity received HIRP at our institution. Local hyperthermia for 1 hour was administered eight to ten times. Radiation therapy (40-60 Gy) was administered at 2 Gy per session. The operation was performed at 2 or 3 weeks after HIRP.
RESULTS: Limb salvage surgery was achieved in 12 patients. No local recurrence was observed during a mean follow-up of 27 months. 7 patients had shown only a partial response to the HIRP. There was no correlation between the histological response and the observed reduction in tumor volume.
CONCLUSIONS: The results of this study suggested that HIRP was an effective local treatment for limb salvage in limb-threatening STS.