[Oxygen-dependent processes in the irradiated organism].

Interaction of oxygen with the X-rayed tissues, chemical substances and elements is one of the main mechanism of radioactive damage. Radiosensibilization by oxygen (oxygen effect) is most highly exhibited under the action of high and moderate radiation doses. However there is only scanty investigations and information about oxygen-dependent processes under low doses of internal and external radiation due to their intricate character. Radiation exerts also a great influence on oxygen metabolism and oxygen consumption level. Oxygen takes active part in post-radiation recovery both at the level of molecules, organelles, cells, tissues, organs and the organism on the whole. The partial pressure of oxygen and its content have a great influence on the action of radioprotectors, anti-radiation therapy and healing methods. Long-term influence of hypoxia at high altitude evokes adaptation changes, stimulates recovery processes in an X-rayed organism, increases resistance to radiation and other noxious factors.