Pressure-Derived Right Ventricular Ejection Fraction During Initial Dual Combination Therapy in Pulmonary Arterial Hypertension.

In patients with pulmonary arterial hypertension, pressure-based right ventricular ejection fraction (RVEF) estimated from routine right heart catheterisation correlated with RVEF from magnetic resonance imaging. A framework combining Weibull distribution-derived theoretical isovolumic pressure and time-varying elastance-derived end-systolic pressure showed the closest correlation and was responsive to initial oral combination therapy.