Journal of pediatric hematology/oncology · 2022
Considerations for Peripheral Blood Stem Cell Apheresis in a Low Body Weight Infant.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Singh Suvir, Kakkar Shruti, Singh Karambir, Kumar Rajesh, Gupta Sonia
Аннотация
INTRODUCTION: Peripheral blood stem cell (PBSC) apheresis in infants (<10 kg body weight) requires specific precautions to prevent periprocedural complications.
CASE REPORT: A 9 month old child was diagnosed with high-risk neuroblastoma and planned for autologous stem cell transplantation after induction chemotherapy. We illustrate the precautions and technical details observed while performing PBSC collection in this patient.
DISCUSSION: Use of continuous flow devices, priming of apheresis circuits, appropriate flow rates and continuous monitoring can help to mitigate several procedure related complications.
CONCLUSIONS: PBSC apheresis in infants (<10 Kg) is safe and feasible with appropriate precautions detailed above.
CASE REPORT: A 9 month old child was diagnosed with high-risk neuroblastoma and planned for autologous stem cell transplantation after induction chemotherapy. We illustrate the precautions and technical details observed while performing PBSC collection in this patient.
DISCUSSION: Use of continuous flow devices, priming of apheresis circuits, appropriate flow rates and continuous monitoring can help to mitigate several procedure related complications.
CONCLUSIONS: PBSC apheresis in infants (<10 Kg) is safe and feasible with appropriate precautions detailed above.