Vaccine · 2009
Viscerotropic disease following yellow fever vaccination in Peru.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Whittembury Alvaro, Ramirez Gladys, Hernández Herminio, Ropero Alba Maria, Waterman Steve, Ticona María, Brinton Margo, Uchuya Jorge, Gershman Mark, Toledo Washington, Staples Erin, Campos Clarense, Martínez Mario, Chang Gwong-Jen J, Cabezas Cesar, Lanciotti Robert, Zaki Sherif, Montgomery Joel M, Monath Thomas, Hayes Edward
Аннотация
Five suspected cases of yellow fever vaccine-associated viscerotropic disease (YEL-AVD) clustered in space and time following a vaccination campaign in Ica, Peru in 2007. All five people received the same lot of 17DD live attenuated yellow fever vaccine before their illness; four of the five died of confirmed YEL-AVD. The surviving case was classified as probable YEL-AVD. Intensive investigation yielded no abnormalities of the implicated vaccine lot and no common risk factors. This is the first described space-time cluster of yellow fever viscerotropic disease involving more than two cases. Mass yellow fever vaccination should be avoided in areas that present extremely low risk of yellow fever.