Annals of palliative medicine · 2026
Patient-reported outcome measures used in studies of palliative surgery in cancer care: a scoping review.
Scoping ReviewСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Wong Bonnie O, Nader Sophie, Wong Jolene Si Min, Low Xinyi Casuarine, Farber Orly N, Liu Jason B, Lilley Elizabeth J
Аннотация
BACKGROUND: Palliative surgery aims to alleviate symptoms and enhance health-related quality of life (HRQL) for patients with incurable cancer. Standardized patient-reported outcome measures (PROMs) are needed to assess effects of interventions, including HRQL from patient perspectives. A previously published systematic review (Wong et al., 2025) identified studies of palliative cancer surgery; the present study is a secondary scoping review to identify and characterize patient-reported measures of HRQL in these studies.
METHODS: We searched PubMed, EMBASE, and CINAHL databases to identify English-language publications (August 1, 2005-December 31, 2023) reporting palliative thoraco-abdominal procedures for cancer patients. Of these, studies reporting patient-reported HRQL outcomes were secondarily analyzed using descriptive and thematic analysis.
RESULTS: Screening of 1,915 unique studies yielded 92 studies of which 16 (17.4%) included a patient-reported HRQL outcome, 11 of which used a total of 13 unique validated PROMs. Five studies which used investigator-developed (non-validated) questionnaires were included to comprehensively map HRQL measures and to identify whether investigator-developed questionnaires captured domains not represented by existing PROMs. Twelve of the identified PROMs were developed or subsequently validated for cancer populations. Items from each PROM were extracted and coded, identifying 62 sub-themes further organized into 6 top-level themes. Content analysis of 242 PROM items across 6 main themes revealed that physical symptoms (76 items, 31.4%) and functional status (50 items, 20.7%) dominate existing measures, while social and structural domains are underrepresented. Fatigue was the most frequently measured sub-theme (11 items), and change in stools, affecting personal relationships, activities of daily living and financial stress were measured by 10 items each. Investigator-developed questionnaires largely overlapped with sub-themes of existing PROMs, identifying only two new sub-themes.
CONCLUSIONS: Despite improved HRQL being the primary goal of palliative surgery, only 16 of 92 studies measured HRQL outcomes, and amidst these studies, significant heterogeneity exists in measurement approaches, with 11 studies using 13 unique PROMs. High heterogeneity in both PROMs used and subthemes measured demonstrates lack of standardization and highlights need for a validated, surgery-specific PROM that captures relevant priorities across HRQL domains.
METHODS: We searched PubMed, EMBASE, and CINAHL databases to identify English-language publications (August 1, 2005-December 31, 2023) reporting palliative thoraco-abdominal procedures for cancer patients. Of these, studies reporting patient-reported HRQL outcomes were secondarily analyzed using descriptive and thematic analysis.
RESULTS: Screening of 1,915 unique studies yielded 92 studies of which 16 (17.4%) included a patient-reported HRQL outcome, 11 of which used a total of 13 unique validated PROMs. Five studies which used investigator-developed (non-validated) questionnaires were included to comprehensively map HRQL measures and to identify whether investigator-developed questionnaires captured domains not represented by existing PROMs. Twelve of the identified PROMs were developed or subsequently validated for cancer populations. Items from each PROM were extracted and coded, identifying 62 sub-themes further organized into 6 top-level themes. Content analysis of 242 PROM items across 6 main themes revealed that physical symptoms (76 items, 31.4%) and functional status (50 items, 20.7%) dominate existing measures, while social and structural domains are underrepresented. Fatigue was the most frequently measured sub-theme (11 items), and change in stools, affecting personal relationships, activities of daily living and financial stress were measured by 10 items each. Investigator-developed questionnaires largely overlapped with sub-themes of existing PROMs, identifying only two new sub-themes.
CONCLUSIONS: Despite improved HRQL being the primary goal of palliative surgery, only 16 of 92 studies measured HRQL outcomes, and amidst these studies, significant heterogeneity exists in measurement approaches, with 11 studies using 13 unique PROMs. High heterogeneity in both PROMs used and subthemes measured demonstrates lack of standardization and highlights need for a validated, surgery-specific PROM that captures relevant priorities across HRQL domains.