Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
Effectiveness of green tea (Camellia sinensis) based mouth rinse on oral health status, pain and quality of life among advanced head and neck cancer patients in a tertiary care centre-a randomized controlled trial.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Roy Meghmaa, Dahiya Ujjwal, Venkatesan Latha, Garg Rakesh, Priya Harsh
Аннотация
PURPOSE: Head and neck cancers (HNC) significantly impact patients' quality of life (QOL), with oral health often being significantly compromised, especially in advanced stages. Green tea, with its known anti-inflammatory and antioxidant properties, may help to improve oral health in these patients. Therefore, this study aims to investigate the effect of green tea-based mouth rinse on oral health status, pain, and QOL of advanced HNC patients.
METHODS: This randomized controlled trial was conducted in the palliative care outpatient department of a tertiary hospital in New Delhi. Then, 64 patients with stage III/IV HNC receiving palliative care were randomly assigned to the experimental and control groups. In addition to usual care, the experimental group used a green tea-based mouth rinse thrice daily for 6 weeks. The study examined oral health status as the primary outcome, which was assessed at baseline and every 2 weeks up to 6 weeks using the Oral Assessment Guide (OAG) and Oral Hygiene Index-Simplified (OHI-S). The secondary outcomes pain and quality of life of the patients were assessed using the Numerical Pain Rating Scale and Oral Health Impact Profile-14 (OHIP-14), respectively.
RESULTS: Repeated measure ANOVA revealed that experimental group had significantly improved OAG-score (F = 34.32, P = < 0.001, ŋp2 = 0.39) and OHI-S-score (F = 5.67, P = < 0.001, ŋp2 = 0.11) over time. However, any significant between-group difference is not found in terms of pain (P = 0.73) and QOL (P = 0.34).
CONCLUSION: Green tea-based mouth rinse was found to be effective in improving the oral health status of advanced HNC patients. Nurses should incorporate such cost-effective options to improve the oral health of cancer patients.
TRIAL REGISTRATION DETAILS: The trial had been registered under the Clinical Trial Registry of India on 17/05/2024. (Registration No: CTRI/2024/05/067571).
METHODS: This randomized controlled trial was conducted in the palliative care outpatient department of a tertiary hospital in New Delhi. Then, 64 patients with stage III/IV HNC receiving palliative care were randomly assigned to the experimental and control groups. In addition to usual care, the experimental group used a green tea-based mouth rinse thrice daily for 6 weeks. The study examined oral health status as the primary outcome, which was assessed at baseline and every 2 weeks up to 6 weeks using the Oral Assessment Guide (OAG) and Oral Hygiene Index-Simplified (OHI-S). The secondary outcomes pain and quality of life of the patients were assessed using the Numerical Pain Rating Scale and Oral Health Impact Profile-14 (OHIP-14), respectively.
RESULTS: Repeated measure ANOVA revealed that experimental group had significantly improved OAG-score (F = 34.32, P = < 0.001, ŋp2 = 0.39) and OHI-S-score (F = 5.67, P = < 0.001, ŋp2 = 0.11) over time. However, any significant between-group difference is not found in terms of pain (P = 0.73) and QOL (P = 0.34).
CONCLUSION: Green tea-based mouth rinse was found to be effective in improving the oral health status of advanced HNC patients. Nurses should incorporate such cost-effective options to improve the oral health of cancer patients.
TRIAL REGISTRATION DETAILS: The trial had been registered under the Clinical Trial Registry of India on 17/05/2024. (Registration No: CTRI/2024/05/067571).