Drug-Induced Immune Thrombocytopenia Secondary to Trimethoprim-Sulfamethoxazole.

We report the case of a 55-year-old male with AIDS who developed severe thrombocytopenia following initiation of trimethoprim-sulfamethoxazole. Despite drug discontinuation and supportive measures, thrombocytopenia persisted, leading to the patient's death. This case highlights the complexities of drug-induced immune thrombocytopenia in immunocompromised patients and emphasizes the risks associated with trimethoprim-sulfamethoxazole.