Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
Distinctive trajectories of symptom burden, activities of daily living, and self-efficacy among patients with advanced cancer receiving care in an acute palliative care unit: a pilot longitudinal study.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Yanai Akihito, Kondo Ken, Otsuka Takahiro, Sato Lisa, Yanai Akiko, Yoshizawa Hina, Koizuka Shiro, Lee Bumsuk
Аннотация
PURPOSE: Patients with advanced cancer experience progressive deterioration in symptom burden, activities of daily living (ADLs), and self-efficacy as they approach the end of life. This pilot longitudinal study aimed to examine the trajectories of these indicators in a palliative care setting and to identify factors associated with survival time.
METHODS: We conducted a prospective observational study of 70 patients with advanced cancer admitted to an acute palliative care unit (APCU) between November 2019 and March 2022. Outcomes included symptom burden, ADLs, and self-efficacy. Scores were reported by the patients or providers during admissions or ambulatory visits. Generalized linear mixed models and generalized additive models were used to analyze trajectories. Multiple regression was used to identify factors associated with time until death.
RESULTS: A total of 227 assessments were performed. Symptom burden followed a U-shaped trajectory, with temporary relief followed by deterioration. ADLs and symptom coping efficacy (SCE) showed a cubic curve pattern, with a stable phase between 15 and 7 weeks. A delayed decline in SCE was observed after symptom worsening. SOB was the only significant predictor of weeks to death (standardized β = -0.251).
CONCLUSION: Distinctive trajectories were observed in symptom burden, ADLs, and self-efficacy, including a temporary stable phase and a delayed decline in SCE. These findings suggest that behavioral support in the APCU may help maintain patient functioning and guide timely care transitions.
METHODS: We conducted a prospective observational study of 70 patients with advanced cancer admitted to an acute palliative care unit (APCU) between November 2019 and March 2022. Outcomes included symptom burden, ADLs, and self-efficacy. Scores were reported by the patients or providers during admissions or ambulatory visits. Generalized linear mixed models and generalized additive models were used to analyze trajectories. Multiple regression was used to identify factors associated with time until death.
RESULTS: A total of 227 assessments were performed. Symptom burden followed a U-shaped trajectory, with temporary relief followed by deterioration. ADLs and symptom coping efficacy (SCE) showed a cubic curve pattern, with a stable phase between 15 and 7 weeks. A delayed decline in SCE was observed after symptom worsening. SOB was the only significant predictor of weeks to death (standardized β = -0.251).
CONCLUSION: Distinctive trajectories were observed in symptom burden, ADLs, and self-efficacy, including a temporary stable phase and a delayed decline in SCE. These findings suggest that behavioral support in the APCU may help maintain patient functioning and guide timely care transitions.