Journal of palliative medicine · 2025
Body Positioning for Dyspnea in Patients with Cancer with Unilateral Pleural Effusion: A Pilot Trial.
СтатьяРандомизированное исследованиеМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
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Kako Jun, Matsuda Yoshinobu, Ikari Tomoo, Suzuki Kozue, Tachikawa Ryo, Matsumoto Yoshihisa, Miwa Satoru, Mori Masanori, Kobayashi Tetsu, Fujimoto Hajime, Tomaru Atsushi, Sumitani Hitoshi, Inoue Akira, Koike Rintaro, Kobayashi Shota, Oyamada Shunsuke, Ariyoshi Keisuke, Yamaguchi Takashi
Аннотация
BACKGROUND: Dyspnea is common in advanced cancer, especially with unilateral pleural effusion. Lateral positioning is widely used, but evidence of effectiveness is limited.
OBJECTIVES: To assess the feasibility and short-term effects of affected-side-down (PLEUR-DOWN) versus affected-side-up (PLEUR-UP) positioning for dyspnea relief.
DESIGN: Multicenter randomized crossover pilot trial.
SETTING/SUBJECTS: Ten patients with cancer with dyspnea were enrolled at seven hospitals in Japan.
METHODS: Patients (numerical rating scale [NRS] ≥ 3) were randomized to two sequences. Each position was maintained for five minutes within a washout period. The primary outcome was feasibility, assessed by completion, absence of carryover/period effects, and adherence. Secondary outcomes included NRS changes, patient preference, and safety.
RESULTS: All patients completed the trial. No significant carryover (p = 0.57) or period effects (p = 0.25) were found. Mean NRS difference favored PLEUR-DOWN (-0.9; p = 0.34). Half preferred PLEUR-DOWN. No adverse events occurred.
CONCLUSIONS: The trial confirmed feasibility and supports further research.
OBJECTIVES: To assess the feasibility and short-term effects of affected-side-down (PLEUR-DOWN) versus affected-side-up (PLEUR-UP) positioning for dyspnea relief.
DESIGN: Multicenter randomized crossover pilot trial.
SETTING/SUBJECTS: Ten patients with cancer with dyspnea were enrolled at seven hospitals in Japan.
METHODS: Patients (numerical rating scale [NRS] ≥ 3) were randomized to two sequences. Each position was maintained for five minutes within a washout period. The primary outcome was feasibility, assessed by completion, absence of carryover/period effects, and adherence. Secondary outcomes included NRS changes, patient preference, and safety.
RESULTS: All patients completed the trial. No significant carryover (p = 0.57) or period effects (p = 0.25) were found. Mean NRS difference favored PLEUR-DOWN (-0.9; p = 0.34). Half preferred PLEUR-DOWN. No adverse events occurred.
CONCLUSIONS: The trial confirmed feasibility and supports further research.