Annals of medicine and surgery (2012) · 2025
Isolated Lung Metastasis Prostate Cancer.
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Mduma Emmanuel, Makwani Hellen, Msuya Said, Shao Eligi D, Ussiri Elijah, Kitinya James
Аннотация
INTRODUCTION AND IMPORTANCE: Prostate cancer is the second most diagnosed malignancy (after lung cancer) in men worldwide. The most common site for metastasis of prostate cancer is bone (84%), followed by distant lymph nodes (10.6%), liver (10.2%), and lung being the least with 9.1%. Isolated lung metastasis is very rare and is present in less than 4.6% of metastatic prostate cancer. This is the first case of de novo isolated lung metastasis of prostate cancer in our setting.
CASE PRESENTATION: We report a case of an 81-year-old male of African ethnicity who was diagnosed with isolated lung metastasis prostate adenocarcinoma. The total prostate specific antigen at the time of diagnosis was 182 ng/ml and grade group 3.
CLINICAL DISCUSSION: The prognosis of prostate cancer patients with pulmonary metastasis is reported to be limited. Prostate cancer patients with lung metastasis have median overall survival of approximately 19 months.
CONCLUSION: Although isolated pulmonary metastasis is rare in prostate cancer, it should not be excluded especially in patients with perineural invasion; however, further investigations are required to exclude metastasis to other sites.
CASE PRESENTATION: We report a case of an 81-year-old male of African ethnicity who was diagnosed with isolated lung metastasis prostate adenocarcinoma. The total prostate specific antigen at the time of diagnosis was 182 ng/ml and grade group 3.
CLINICAL DISCUSSION: The prognosis of prostate cancer patients with pulmonary metastasis is reported to be limited. Prostate cancer patients with lung metastasis have median overall survival of approximately 19 months.
CONCLUSION: Although isolated pulmonary metastasis is rare in prostate cancer, it should not be excluded especially in patients with perineural invasion; however, further investigations are required to exclude metastasis to other sites.