Hepatitis monthly · 2015
Hepatitis E Virus Seroprevalence Among Blood Donors in Bushehr, South of Iran.
СтатьяНазвание и аннотация: Перевод в очереди
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Naeimi Behrouz, Mazloom Kalimani Farnaz, Pourfatolah Ali Akbar, Azimzadeh Masoud, Mankhian Alireza, Akbarzadeh Samad, Hajiani Gholamreza, Kooshesh Faramarz, Khamisipour Gholamreza
Аннотация
BACKGROUND: Although so far several studies have determined the hepatitis E virus (HEV) prevalence in some parts of Iran, no data exists regarding the HEV seroprevalence in Bushehr province as the southernmost point in Iran yet.
OBJECTIVES: The aim of this study was to evaluate the seroprevalence of anti-HEV IgG among the blood donors in Bushehr.
PATIENTS AND METHODS: A total of 628 blood donor samples were collected from September to October 2013, after obtaining informed written consents, and analyzed for the presence of anti-HEV IgG using commercial HEV enzyme-linked immunosorbent assay (ELISA) kit. All the samples were tested by two ELISA kits and evaluated for liver function test.
RESULTS: Overall, 105 (16.7%) blood samples were positive for HEV-specific-IgG antibodies, while 523 (83.8%) were negative. The presence of anti-HEV IgG was not associated with gender; however, it was correlated with age. It was indicated that the anti-HEV prevalence increases by age and there was a significant difference between the age groups regarding HEV seropositivity.
CONCLUSIONS: High HEV seroprevalence (16.7%) was observed among the blood donors in Bushehr province. It appears that exposure to HEV increases with age; although, more people should be examined.
OBJECTIVES: The aim of this study was to evaluate the seroprevalence of anti-HEV IgG among the blood donors in Bushehr.
PATIENTS AND METHODS: A total of 628 blood donor samples were collected from September to October 2013, after obtaining informed written consents, and analyzed for the presence of anti-HEV IgG using commercial HEV enzyme-linked immunosorbent assay (ELISA) kit. All the samples were tested by two ELISA kits and evaluated for liver function test.
RESULTS: Overall, 105 (16.7%) blood samples were positive for HEV-specific-IgG antibodies, while 523 (83.8%) were negative. The presence of anti-HEV IgG was not associated with gender; however, it was correlated with age. It was indicated that the anti-HEV prevalence increases by age and there was a significant difference between the age groups regarding HEV seropositivity.
CONCLUSIONS: High HEV seroprevalence (16.7%) was observed among the blood donors in Bushehr province. It appears that exposure to HEV increases with age; although, more people should be examined.