Zhonghua zhong liu za zhi [Chinese journal of oncology] · 1998
[Detection of type 6 human herpesvirus (HHV-6) specific DNA sequence in lymphoma tissues by PCR].
Аннотация на английскомСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Pan F, Lü H, Fan H
Аннотация
OBJECTIVE: To study the relationship between human herpesvirus-6 (HHV-6) and lymphoma in China.
METHODS: The specimens of paraffin-embedded lymphoma tissue, leukemia cell lines and normal blood donor peripheral blood lymphocytes(PBL) were examined for the presence of HHV-6 DNA sequence by polymerase chain reaction (PCR).
RESULTS: Of the 52 cases lymphoma studied, HHV-6 DNA sequence was detected in 21 cases; of 43 normal PBL, HHV-6 DNA sequence was detected in 8 cases. The difference was statistically significant (P < 0.05). HHV-6 DNA sequence was also present in two leukemia cell lines.
CONCLUSION: The results suggest that HHV-6 may be related to lymphoma in China.
METHODS: The specimens of paraffin-embedded lymphoma tissue, leukemia cell lines and normal blood donor peripheral blood lymphocytes(PBL) were examined for the presence of HHV-6 DNA sequence by polymerase chain reaction (PCR).
RESULTS: Of the 52 cases lymphoma studied, HHV-6 DNA sequence was detected in 21 cases; of 43 normal PBL, HHV-6 DNA sequence was detected in 8 cases. The difference was statistically significant (P < 0.05). HHV-6 DNA sequence was also present in two leukemia cell lines.
CONCLUSION: The results suggest that HHV-6 may be related to lymphoma in China.