Медицинская библиотека · The Journal of infectious diseases · 2018

Development of Mobile Laboratory for Viral Hemorrhagic Fever Detection in Africa.

Weidmann Manfred, Faye Ousmane, Faye Oumar, Abd El Wahed Ahmed, Patel Pranav, Batejat Christophe, Manugerra Jean Claude, Adjami Aimee, Niedrig Matthias, Hufert Frank T, Sall Amadou A

СтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

BACKGROUND

A mobile laboratory transportable on commercial flights was developed to enable local response to viral hemorrhagic fever outbreaks.

METHODS

The development progressed from use of mobile real-time reverse-transcription polymerase chain reaction to mobile real-time recombinase polymerase amplification. In this study, we describe various stages of the mobile laboratory development.

RESULTS

A brief overview of mobile laboratory deployments, which culminated in the first on-site detection of Ebola virus disease (EVD) in March 2014, and their successful use in a campaign to roll back EVD cases in Conakry in the West Africa Ebola virus outbreak are described.

CONCLUSIONS

The developed mobile laboratory successfully enabled local teams to perform rapid disgnostic testing for viral hemorrhagic fever.

Для цитирования: Weidmann Manfred, Faye Ousmane, Faye Oumar, Abd El Wahed Ahmed, Patel Pranav, Batejat Christophe, Manugerra Jean Claude, Adjami Aimee, Niedrig Matthias, Hufert Frank T, Sall Amadou A. Development of Mobile Laboratory for Viral Hemorrhagic Fever Detection in Africa.. The Journal of infectious diseases. 2018. DOI: 10.1093/infdis/jiy362.

Предметные рубрики MeSH

Africa, Western Ebolavirus Hemorrhagic Fever, Ebola Humans Laboratories Mobile Health Units Molecular Typing Point-of-Care Systems RNA, Viral Real-Time Polymerase Chain Reaction

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