Obstetrics and gynecology · 1998
Encouraging response of an advanced steroid-cell tumor to GnRH agonist therapy.
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Brewer C A, Shevlin D
Аннотация
BACKGROUND: Chemotherapy for steroid tumors of unspecified type has met with limited success and the overall prognosis has been poor.
CASE: A patient with a virilizing steroid tumor, otherwise unspecified, with demonstrated progressive disease after surgical debulking. Treatment with multiagent chemotherapy failed, but the patient subsequently had a robust response to GnRH agonist therapy.
CONCLUSION: GnRH analogue treatment should be considered prior to cytotoxic chemotherapy in cases of steroid tumor, not otherwise specified.
CASE: A patient with a virilizing steroid tumor, otherwise unspecified, with demonstrated progressive disease after surgical debulking. Treatment with multiagent chemotherapy failed, but the patient subsequently had a robust response to GnRH agonist therapy.
CONCLUSION: GnRH analogue treatment should be considered prior to cytotoxic chemotherapy in cases of steroid tumor, not otherwise specified.