Solid-Organ Transplantation From Deceased and Living Donors With Cancer or a History of Cancer.

With the introduction of effective screening strategies, cancers are being diagnosed at earlier stages and cumulative survival rates of patients with cancer are increasing. On the other hand, the number of people who would benefit from a solid-organ transplant is also increasing. Continued organ shortages have resulted in evaluations of further potential donors, including patients with cancer. The literature related to donor- derived malignancy transmission is mostly limited to case reports, data registry series, and retrospective studies. According to data from the literature, organs from deceased and living donors with some types of current or past cancers may be safely used for transplant. The risk of cancer transmission must be balanced against the risk of a patient dying or becoming clinically worse during the period of waiting for a transplant on a case-by-case basis. Current transplant protocols are only allowed for patients with central nervous system tumors in Turkey and most other countries. However, some other patients with a history of cancer can be acceptable as organ donors. This review has summarized data from the literature.