Life-Cycle Performance of Poly(methyl methacrylate) in Digital Dentistry: A Critical Review of Material Efficiency, Waste Generation, and Circularity.

Poly(methyl methacrylate) (PMMA) is one of the most widely used polymeric biomaterials in prosthodontics and digital dentistry because of their clinical reliability and compatibility with computer-aided design/computer-aided manufacturing (CAD/CAM). Its widespread use raises questions regarding material consumption, manufacturing waste, recyclability, and circularity. A critical narrative review supported by a structured literature search was conducted. PubMed, Scilit, OpenAlex, and ScienceDirect were searched for English-language literature published from January 2000 to June 2026. Targeted Google Scholar searches, cross-referencing, standards, and official technical sources supplemented the search. Evidence was organized according to its directness to dental PMMA and synthesized thematically. Prepolymerized CAD/CAM PMMA provides consistent material quality and generally improved mechanical performance compared with conventionally processed PMMA; however, subtractive manufacturing generates disc remnants, milling particles, and polishing residues. Mechanical recycling and depolymerization demonstrate technical recovery potential, although evidence specific to heterogeneous dental waste streams, environmental performance, and clinical-grade reuse remains limited. Technical recyclability should not be automatically equated with a viable circular economy or a net environmental benefit. Future research should quantify dental PMMA waste, establish effective collection and recovery pathways, and integrate life-cycle assessments with clinical performance and safety standards.