The Journal of infectious diseases · 2017
Development, Use, and Impact of a Global Laboratory Database During the 2014 Ebola Outbreak in West Africa.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Durski Kara N, Singaravelu Shalini, Teo Junxiong, Naidoo Dhamari, Bawo Luke, Jambai Amara, Keita Sakoba, Yahaya Ali Ahmed, Muraguri Beatrice, Ahounou Brice, Katawera Victoria, Kuti-George Fredson, Nebie Yacouba, Kohar T Henry, Hardy Patrick Jowlehpah, Djingarey Mamoudou Harouna, Kargbo David, Mahmoud Nuha, Assefa Yewondwossen, Condell Orla, N'Faly Magassouba, Van Gurp Leon, Lamanu Margaret, Ryan Julia, Diallo Boubacar, Daffae Foday, Jackson Dikena, Malik Fayyaz Ahmed, Raftery Philomena, Formenty Pierre
Аннотация
BACKGROUND: The international impact, rapid widespread transmission, and reporting delays during the 2014 Ebola outbreak in West Africa highlighted the need for a global, centralized database to inform outbreak response. The World Health Organization and Emerging and Dangerous Pathogens Laboratory Network addressed this need by supporting the development of a global laboratory database.
METHODS: Specimens were collected in the affected countries from patients and dead bodies meeting the case definitions for Ebola virus disease. Test results were entered in nationally standardized spreadsheets and consolidated onto a central server.
RESULTS: From March 2014 through August 2016, 256343 specimens tested for Ebola virus disease were captured in the database. Thirty-one specimen types were collected, and a variety of diagnostic tests were performed. Regular analysis of data described the functionality of laboratory and response systems, positivity rates, and the geographic distribution of specimens.
CONCLUSION: With data standardization and end user buy-in, the collection and analysis of large amounts of data with multiple stakeholders and collaborators across various user-access levels was made possible and contributed to outbreak response needs. The usefulness and value of a multifunctional global laboratory database is far reaching, with uses including virtual biobanking, disease forecasting, and adaption to other disease outbreaks.
METHODS: Specimens were collected in the affected countries from patients and dead bodies meeting the case definitions for Ebola virus disease. Test results were entered in nationally standardized spreadsheets and consolidated onto a central server.
RESULTS: From March 2014 through August 2016, 256343 specimens tested for Ebola virus disease were captured in the database. Thirty-one specimen types were collected, and a variety of diagnostic tests were performed. Regular analysis of data described the functionality of laboratory and response systems, positivity rates, and the geographic distribution of specimens.
CONCLUSION: With data standardization and end user buy-in, the collection and analysis of large amounts of data with multiple stakeholders and collaborators across various user-access levels was made possible and contributed to outbreak response needs. The usefulness and value of a multifunctional global laboratory database is far reaching, with uses including virtual biobanking, disease forecasting, and adaption to other disease outbreaks.