Khirurgiia · 2007
[Importance of conservation media for organ conservation of human liver in case of cadaveric organ explantation].
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Ionkov A, Dimitrova V, Budzhema K
Аннотация
PURPOSE: to estimate results from application of two kinds conservation solutions in the organ preservation process of human liver in case of cadaveric organ explantation.
MATERIALS AND METHODS: survey comprises 260 cadaver donors - males 168 (68%), mean age 37 +/- 1 years and 92 females 41 +/- 1 years. Average conservation period of donor's liver, reviewed by average time of organ's cold ischemia, was 9 hours 36 min +/- 11 min. Minimal duration period - 3 hours 53 min, maximal duration period - 15 hours 9 min. Average duration period 10 hours 7 min. UW solution was used for perfusion in 188 donors, and Celsior solution - in 72 cases.
RESULTS: Comparison of graft's cumulative survival time in studied groups shows 78% survival rate for 52 weeks period in Celsior solution group and 65% for UW solution. Retrieved data was analyzed by descriptive, parametric, non-parametric, dispersive, logistic regressive and other methods.
CONCLUSION: Data are statistically comparable. In practice this means, that both solutions could be applied with equal results and without risk of perioperative failure, especially using Celsior solution.
MATERIALS AND METHODS: survey comprises 260 cadaver donors - males 168 (68%), mean age 37 +/- 1 years and 92 females 41 +/- 1 years. Average conservation period of donor's liver, reviewed by average time of organ's cold ischemia, was 9 hours 36 min +/- 11 min. Minimal duration period - 3 hours 53 min, maximal duration period - 15 hours 9 min. Average duration period 10 hours 7 min. UW solution was used for perfusion in 188 donors, and Celsior solution - in 72 cases.
RESULTS: Comparison of graft's cumulative survival time in studied groups shows 78% survival rate for 52 weeks period in Celsior solution group and 65% for UW solution. Retrieved data was analyzed by descriptive, parametric, non-parametric, dispersive, logistic regressive and other methods.
CONCLUSION: Data are statistically comparable. In practice this means, that both solutions could be applied with equal results and without risk of perioperative failure, especially using Celsior solution.