[Importance of conservation media for organ conservation of human liver in case of cadaveric organ explantation].

PURPOSE: to estimate results from application of two kinds conservation solutions in the organ preservation process of human liver in case of cadaveric organ explantation.

MATERIALS AND

METHODS

survey comprises 260 cadaver donors - males 168 (68%), mean age 37 +/- 1 years and 92 females 41 +/- 1 years. Average conservation period of donor's liver, reviewed by average time of organ's cold ischemia, was 9 hours 36 min +/- 11 min. Minimal duration period - 3 hours 53 min, maximal duration period - 15 hours 9 min. Average duration period 10 hours 7 min. UW solution was used for perfusion in 188 donors, and Celsior solution - in 72 cases.

RESULTS

Comparison of graft's cumulative survival time in studied groups shows 78% survival rate for 52 weeks period in Celsior solution group and 65% for UW solution. Retrieved data was analyzed by descriptive, parametric, non-parametric, dispersive, logistic regressive and other methods.

CONCLUSION

Data are statistically comparable. In practice this means, that both solutions could be applied with equal results and without risk of perioperative failure, especially using Celsior solution.