Cornea · 2007
In situ versus whole-globe harvesting of corneal tissue from remote donor sites: effects on initial tissue quality.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Rootman Dan B, Wankiewicz Ellen, Sharpen Linda, Baxter Stephanie A
Аннотация
PURPOSE: There are 2 methods of corneal tissue procurement currently in widespread use: in situ extraction of the corneal button directly to preservation media and whole-globe enucleation of eyes with removal of the button to preservation media at a later time. This study evaluates the effects of these 2 procurement procedures on the initial quality of donor corneal tissue.
METHODS: Slit-lamp examination results and endothelial cell counts were compared for a total of 468 donor corneas harvested at 2 remote locations: one where in situ procurement was practiced and the other that used whole-globe enucleation procedures.
RESULTS: In both univariate and multivariate analysis, in situ corneas were found to have a lower incidence of moderate or severe haze and folds in Descemet membrane. No differences in mean endothelial cell counts were noted between the 2 populations of donated tissue.
CONCLUSIONS: In situ procurement of corneal tissue results in higher initial corneal tissue quality than whole-globe procedures.
METHODS: Slit-lamp examination results and endothelial cell counts were compared for a total of 468 donor corneas harvested at 2 remote locations: one where in situ procurement was practiced and the other that used whole-globe enucleation procedures.
RESULTS: In both univariate and multivariate analysis, in situ corneas were found to have a lower incidence of moderate or severe haze and folds in Descemet membrane. No differences in mean endothelial cell counts were noted between the 2 populations of donated tissue.
CONCLUSIONS: In situ procurement of corneal tissue results in higher initial corneal tissue quality than whole-globe procedures.