The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2004
Donor-recipient gender mismatch in lung transplantation: impact on obliterative bronchiolitis and survival.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Roberts David H, Wain John C, Chang Yuchiao, Ginns Leo C
Аннотация
BACKGROUND: Because of the shortage of donor lungs, liberalization of donor selection criteria in terms of age, gas exchange, and smoking history has been proposed.
METHODS: We evaluated a single-institution population of lung transplant recipients (n = 98) for donor-recipient gender matching. We measured overall survival, time to acute allograft rejection, and time to development of obliterative bronchiolitis (OB).
RESULTS: We found significant improvement in overall survival for gender-mismatched donor and recipient pairs (p = 0.078) and a significantly shorter OB-free period for male donor and female recipient pairs (p = 0.017).
CONCLUSION: These findings suggest that donor organ allocation based on gender may affect long-term survival and other outcomes after lung transplantation.
METHODS: We evaluated a single-institution population of lung transplant recipients (n = 98) for donor-recipient gender matching. We measured overall survival, time to acute allograft rejection, and time to development of obliterative bronchiolitis (OB).
RESULTS: We found significant improvement in overall survival for gender-mismatched donor and recipient pairs (p = 0.078) and a significantly shorter OB-free period for male donor and female recipient pairs (p = 0.017).
CONCLUSION: These findings suggest that donor organ allocation based on gender may affect long-term survival and other outcomes after lung transplantation.