Video Demonstration of ABCA12-Related Harlequin Ichthyosis in a Low-Resource Setting: Case Report and Review of Early Management Challenges.

Harlequin ichthyosis is a rare, life-threatening neonatal dermatologic emergency that can be confidently diagnosed clinically at birth. Prompt recognition and early supportive management-including thermoregulation, fluid balance, infection prevention, and intensive skin care-are crucial determinants of survival, especially in low-resource settings where diagnostic and therapeutic options are limited.