Persistent Burkholderia cepacia Bacteremia in Reconstructive Surgery: Resistance to Ceftazidime/Avibactam and Co-Trimoxazole With Risk of Infective Endocarditis-A Case Report.

Persistent Burkholderia cepacia bacteremia in soft tissue infections creates diagnostic and therapeutic challenges due to its resistance profile and potential for endovascular involvement. Early culture-guided therapy, multidisciplinary coordination, and vigilance for complications, such as infective endocarditis, are essential for achieving favorable outcomes in reconstructive surgical settings.