Inhibition of butyrylcholinesterase in a population exposed to insecticides during a campaign against Aedes aegypti.

BACKGROUND

Chemical control remains a widely used strategy to reduce morbidity from vector-borne diseases such as dengue. However, the potential health risks to exposed populations necessitates ongoing monitoring, particularly due to the toxicity and volume of insecticides employed.

METHODS

This study assessed butyrylcholinesterase activity in residents of a city in southern Mexico during distinct periods of exposure to carbamate and organophosphate insecticides.

RESULTS

A statistically significant inhibition of enzymatic activity was observed during the rainy season, which coincided with an increase in insecticide application.

CONCLUSIONS

These findings highlight the need for public health authorities to implement preventative measures aimed at minimizing poisoning risks associated with vector control activities.