British journal of sports medicine · 2026
Over-the-counter analgesics improve postconcussion symptoms and recovery: findings from the Concussion Assessment, Research and Education (CARE) Consortium.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Arnold Kyle, Mukherjee Anish, Kim Yeo Won, Rosenlind Kira, Broglio Steven, McCrea Michael A, McAllister Thomas, Sharma Tara Lani
Аннотация
OBJECTIVES: To determine if postinjury over-the-counter (OTC) analgesic use, along with type and timing of medications, is associated with improved concussion recovery and symptom severity in National Collegiate Athletic Association (NCAA) and non-NCAA athletes.
METHODS: This cohort study was conducted by the NCAA and Department of Defense Concussion Assessment, Research and Education Consortium from 2014 to 2022. Athletes included were those who used OTC analgesics for <3 days and those who did not use OTC analgesics postinjury. OTC analgesic type was categorised as acetaminophen (n=463), non-steroidal anti-inflammatory drugs (NSAIDs, n=77), both (n=34) and no OTC analgesic use (n=848). Concussion recovery was measured as days from injury to clearance to return to unrestricted play (time to URTP). Symptom and headache severity were derived from the Sports Concussion Assessment Tool third edition (SCAT3) taken at baseline, <48 hours postinjury (median <1 day postinjury) and 3 days postinjury (median 3 days postinjury).
RESULTS: There were 576 who did and 848 who did not use OTC analgesics included in the study. OTC analgesic use was associated with a higher rate of URTP adjusted HR (aHR) (aHR 1.25 (95% CI 1.11 to 1.39)) and lower 3-day postinjury SCAT3 symptom ([Formula: see text]=0.70 (95% CI 0.62 to 0.79)) and headache ([Formula: see text]0.89 (95% CI 0.84 to 0.94)) severity scores. Early OTC analgesic use (≤2 days) was associated with a higher rate of URTP compared with delayed (>2 days) use after injury (HR 1.36 (95% CI 1.22 to 1.53)). There was little association among acetaminophen, NSAIDs and both for outcome measures.
CONCLUSIONS: This study shows that OTC analgesic use postinjury is associated with lower symptom severity and a faster recovery after concussion.
METHODS: This cohort study was conducted by the NCAA and Department of Defense Concussion Assessment, Research and Education Consortium from 2014 to 2022. Athletes included were those who used OTC analgesics for <3 days and those who did not use OTC analgesics postinjury. OTC analgesic type was categorised as acetaminophen (n=463), non-steroidal anti-inflammatory drugs (NSAIDs, n=77), both (n=34) and no OTC analgesic use (n=848). Concussion recovery was measured as days from injury to clearance to return to unrestricted play (time to URTP). Symptom and headache severity were derived from the Sports Concussion Assessment Tool third edition (SCAT3) taken at baseline, <48 hours postinjury (median <1 day postinjury) and 3 days postinjury (median 3 days postinjury).
RESULTS: There were 576 who did and 848 who did not use OTC analgesics included in the study. OTC analgesic use was associated with a higher rate of URTP adjusted HR (aHR) (aHR 1.25 (95% CI 1.11 to 1.39)) and lower 3-day postinjury SCAT3 symptom ([Formula: see text]=0.70 (95% CI 0.62 to 0.79)) and headache ([Formula: see text]0.89 (95% CI 0.84 to 0.94)) severity scores. Early OTC analgesic use (≤2 days) was associated with a higher rate of URTP compared with delayed (>2 days) use after injury (HR 1.36 (95% CI 1.22 to 1.53)). There was little association among acetaminophen, NSAIDs and both for outcome measures.
CONCLUSIONS: This study shows that OTC analgesic use postinjury is associated with lower symptom severity and a faster recovery after concussion.