Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2026
Comparison of complications after cholecystectomy between bariatric and nonbariatric patients: a retrospective single-center cohort study.
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Hoozemans Jacqueline Bernadette, Franken Rutger Jan, de Brauw Louis Maurits, Nieuwdorp Max, Gerdes Victor E A
Аннотация
BACKGROUND: The global incidence of gallstone disease is rising in parallel with increasing obesity rates. Previous studies indicate a higher complication risk for cholecystectomy performed in patients with previous bariatric surgery; however, this is debated.
OBJECTIVES: The objective is to compare the complication rate of cholecystectomy between patients with previous bariatric surgery and nonbariatric controls. The primary objective is 30-day complication rate, and secondary objectives are 30-day to 1-year complication rates and presence of persistent or new abdominal complaints.
SETTING: A retrospective cohort study conducted at a hospital in the Netherlands, including all patients who underwent cholecystectomy between 2019 and 2022 after previous bariatric surgery, with time-matched nonbariatric cholecystectomy controls.
METHODS: A 1:2 comparison between the abovementioned groups.
RESULTS: The bariatric surgery cohort included 133 patients, and the control cohort included 259 patients. The primary outcome of 30-day complications after cholecystectomy was higher among postbariatric cases than among controls (33.1% versus 16.6%; P < .001; χ2 test, OR, 2.48; 95% CI, 1.52-4.05). Complications between 30 days and 1 year were also significantly higher among postbariatric cases (18.6% versus 6.2%, P < .001). There was no clear difference in major complications (6.0% versus 4.6%, P = .73). Abdominal complaints at 1 year after cholecystectomy were significantly higher in postbariatric cases than in nonbariatric controls (32.6% versus 11.2%, P < .001).
CONCLUSIONS: Complications after cholecystectomy were more frequent in patients with previous bariatric surgery than in nonbariatric controls. It is important for clinicians to be aware of a higher complication rate after laparoscopic cholecystectomy following bariatric surgery.
OBJECTIVES: The objective is to compare the complication rate of cholecystectomy between patients with previous bariatric surgery and nonbariatric controls. The primary objective is 30-day complication rate, and secondary objectives are 30-day to 1-year complication rates and presence of persistent or new abdominal complaints.
SETTING: A retrospective cohort study conducted at a hospital in the Netherlands, including all patients who underwent cholecystectomy between 2019 and 2022 after previous bariatric surgery, with time-matched nonbariatric cholecystectomy controls.
METHODS: A 1:2 comparison between the abovementioned groups.
RESULTS: The bariatric surgery cohort included 133 patients, and the control cohort included 259 patients. The primary outcome of 30-day complications after cholecystectomy was higher among postbariatric cases than among controls (33.1% versus 16.6%; P < .001; χ2 test, OR, 2.48; 95% CI, 1.52-4.05). Complications between 30 days and 1 year were also significantly higher among postbariatric cases (18.6% versus 6.2%, P < .001). There was no clear difference in major complications (6.0% versus 4.6%, P = .73). Abdominal complaints at 1 year after cholecystectomy were significantly higher in postbariatric cases than in nonbariatric controls (32.6% versus 11.2%, P < .001).
CONCLUSIONS: Complications after cholecystectomy were more frequent in patients with previous bariatric surgery than in nonbariatric controls. It is important for clinicians to be aware of a higher complication rate after laparoscopic cholecystectomy following bariatric surgery.