Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
Pupil size measurements with two multifunctional devices based on different technologies and an infrared based pupillometer.
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Davidova Petra, Bucur Julian, Achourak Asma, Wend Jakob, Kaiser Klemens Paul, Kohnen Thomas
Аннотация
PURPOSE: To compare inter- and intra-device agreement of pupil size (PS) measurements of an aberrometer/coherence interferometer/tomographer (Pentacam AXL Wave (OCULUS)), optical coherence tomographer/placido topographer (MS-39, (CSO/Schwind)) and an infrared based pupillometer (PupilX (Albomed)).
METHODS: In this prospective study, PS of healthy eyes was measured with Pentacam without (WO) and with glare (WG), PupilX in 0, 0.06, 0.12, 4 and 64 lx and MS-39 in 0.04, 4 and 50 lx three times each. Scotopic conditions were defined as WO and ≤ 0.12 lx, mesopic as 4 lx and photopic as WG, 50 and 64 lx. Measurements were compared per lighting condition.
RESULTS: Thirty-seven eyes of 37 participants (mean age 30.8 years ± 9.1 years) were included. Pentacam WG and PupilX at 64 lx showed the lowest inter-device difference and had the only non-significant difference (p = 0.204). The second lowest mean difference was between Pentacam WO and PupilX at 0.06 lx where significance was also not met (p = 0.05). Pentacam WO and PupilX at 0 lx showed the highest inter-device difference (p < 0.001). The lowest intra-device difference (IDD) for scotopic conditions was 0.19 mm (standard deviation (SD): 0.17 mm) with PupilX at 0 lx. In mesopic conditions, the lowest IDD was 0.2 mm (SD: 0.15 mm) with MS-39, in photopic conditions 0.16 mm (SD: 0.11 mm) with PupilX.
CONCLUSION: Pentacam showed close-to-acceptable agreement with PupilX in photopic conditions. In the other conditions significant differences were found, which applied for MS-39 and PupilX for all illumination levels. All three devices showed excellent intra-device repeatability for all illuminations levels.
METHODS: In this prospective study, PS of healthy eyes was measured with Pentacam without (WO) and with glare (WG), PupilX in 0, 0.06, 0.12, 4 and 64 lx and MS-39 in 0.04, 4 and 50 lx three times each. Scotopic conditions were defined as WO and ≤ 0.12 lx, mesopic as 4 lx and photopic as WG, 50 and 64 lx. Measurements were compared per lighting condition.
RESULTS: Thirty-seven eyes of 37 participants (mean age 30.8 years ± 9.1 years) were included. Pentacam WG and PupilX at 64 lx showed the lowest inter-device difference and had the only non-significant difference (p = 0.204). The second lowest mean difference was between Pentacam WO and PupilX at 0.06 lx where significance was also not met (p = 0.05). Pentacam WO and PupilX at 0 lx showed the highest inter-device difference (p < 0.001). The lowest intra-device difference (IDD) for scotopic conditions was 0.19 mm (standard deviation (SD): 0.17 mm) with PupilX at 0 lx. In mesopic conditions, the lowest IDD was 0.2 mm (SD: 0.15 mm) with MS-39, in photopic conditions 0.16 mm (SD: 0.11 mm) with PupilX.
CONCLUSION: Pentacam showed close-to-acceptable agreement with PupilX in photopic conditions. In the other conditions significant differences were found, which applied for MS-39 and PupilX for all illumination levels. All three devices showed excellent intra-device repeatability for all illuminations levels.