A daily-durable wearable sweat biosensing device with robust reticular conductive biogel interface.

Wearable biosensing devices are essential for managing chronic diseases at home. However, their clinical translation has been hindered by the poor durability and stability of biosensors during long-term use in real-world scenarios. Here, we report a daily-durable wearable electrochemical biosensor array by encapsulating ZIF-90@enzymes within a conductive gel matrix to form a robust reticular biogel interface for continuous analysis of sweat glucose and lactate. The wearable biosensors exhibit exceptional environmental adaptability and durability, retaining >95 % sensitivity after summer outdoor exposure for 10 h and >85 % sensitivity after 1000 bends. In addition, they also demonstrate excellent pH and temperature tolerance, and the room-temperature storage stability of 140 days. By integrating the biosensor array with a paper-based sweat collector and a printed circuit board, the proposed wearable device enables on-body sweat analysis during both vigorous exercise (e.g., running) and daily activities, showing its application prospects in routine health monitoring.