Synthesis, structure, catalytic and cytotoxic activities of chlorido-(5-nitro-quinolin-8-olato-κ2 N,O)(tri-cyclo-hexyl-phosphine-κP)platinum(II).

The title complex, [Pt(C10H5N2O3)Cl(C18H33P)], was synthesized by the reaction of [PtCl(C10H5N2O3)(η2-C2H4)] and PCy3 at room temperature for 2 h with a yield of 80%. The deprotonated 5-nitro-quinoline-8-ol (C10H5N2O3 -) anion coordinates to the metal atom in a bidentate mode via its N and O atoms with a N-Pt-O bite angle of 80.0 (3)°. The tri-cyclo-hexyl-phosphine P atom is in a trans position with respect to the N atom in the square-planar coordination environment of the metal atom. The packing features zigzag chains linked by C-H⋯O inter-actions and continuous channels occupied by disordered solvent mol-ecules, both running in the a-axis direction. The complex shows weak activity against four cancer cell lines with IC50 values > 120 µM, but significant catalytic ability and selectivity for hydro-silylation between phenyl-acetyl-ene and tri-ethyl-silane.