Projecting high-level dengue increases during low-incidence months in a large endemic urban area.

BACKGROUND

Climate change projections impact dengue transmission in tropical regions, creating diverse and complex public health challenges. The aim of this study was to project future seasonal dengue incidence in a large tropical urban area of Brazil, where dengue is endemic, by systematically analyzing climatic and dengue case time series.

METHODS

An epidemiological dengue model was developed using time series analysis techniques and forced with statistical downscaling from various Coupled Model Intercomparison Project Phase 6 (CMIP6) climate models based on Shared Socioeconomic Pathway (SSP) scenarios for the late twenty-first century (2071-2100). The ecological time-series investigation analyzed 193 618 dengue cases from January 2008 to December 2018. Statistical downscaling transformed low-resolution Global Climate Models' outputs into high-resolution data, based on a 30-y climate baseline.

RESULTS

The results indicated significant climate changes in seasonal temperature and precipitation by the end of the century. Under both SSP2-4.5 and SSP5-8.5 scenarios, substantial increases in dengue cases are projected during current low-incidence months, resulting in a reduced seasonality of dengue.

CONCLUSIONS

The findings represent considerable challenges for future public health systems, which may face sustained high levels of dengue incidence throughout the year.