Environmental research · 2025
Co-exposure to air pollution and noise from traffic and their association with cognitive impairment in adults. Systematic review.
СтатьяСистематический обзорНазвание и аннотация: Перевод в очереди
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Hildt C, Tzivian L, Ogurtsova K, Hoffmann B
Аннотация
BACKGROUND: Both air pollution (AP) and traffic noise are known as being independently associated with adverse cognitive outcomes. Although traffic is known to be a common source of both types of exposures, there is limited evidence on how these exposures interact and mutually confound cognitive function.
OBJECTIVE: Investigate how long-term AP and traffic noise are interrelated in their association with and effect on cognitive impairment, with a specific focus on possible effect modification (EM)/interaction and mutual confounding.
METHODS: All English-language studies meeting the eligibility criteria were considered. We included all studies on MEDLINE, Web of Science, and LUDOK database of Swiss TPH published until April 17, 2024. The quality of evidence was evaluated according to the Office of Health Assessment and Translation (OHAT) system.
RESULTS: Nineteen studies on the long-term effects of co-exposure to AP and traffic noise on cognitive function were identified. All studies showed moderate external validity. The overall confidence in the evidence was low to moderate. Effect estimates remained stable after mutual adjustment for AP and noise across most cognitive outcomes. This pattern was consistent for both exposures. Three studies with high exposure levels reported evidence of EM and interaction, while two studies with lower exposure levels observed no interactions.
CONCLUSION: Studies analysing co-exposures require more transparent reporting of changes in effect estimates before and after adjustment, as well as an additional examination for possible EM and interaction.
OBJECTIVE: Investigate how long-term AP and traffic noise are interrelated in their association with and effect on cognitive impairment, with a specific focus on possible effect modification (EM)/interaction and mutual confounding.
METHODS: All English-language studies meeting the eligibility criteria were considered. We included all studies on MEDLINE, Web of Science, and LUDOK database of Swiss TPH published until April 17, 2024. The quality of evidence was evaluated according to the Office of Health Assessment and Translation (OHAT) system.
RESULTS: Nineteen studies on the long-term effects of co-exposure to AP and traffic noise on cognitive function were identified. All studies showed moderate external validity. The overall confidence in the evidence was low to moderate. Effect estimates remained stable after mutual adjustment for AP and noise across most cognitive outcomes. This pattern was consistent for both exposures. Three studies with high exposure levels reported evidence of EM and interaction, while two studies with lower exposure levels observed no interactions.
CONCLUSION: Studies analysing co-exposures require more transparent reporting of changes in effect estimates before and after adjustment, as well as an additional examination for possible EM and interaction.