Journal of computer assisted tomography · 1998
Dynamic helical CT of breast tumors.
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Sardanelli F, Calabrese M, Zandrino F, Melani E, Parodi R, Imperiale A, Massa T, Parodi G, Canavese G
Аннотация
PURPOSE: The purpose of our study was to test dynamic helical CT (hCT) in the evaluation of breast tumors.
METHOD: Thirty-six patients with 39 suspected lesions underwent breast hCT before and 1, 3, and 8 min after intravenous contrast medium administration. A marked enhancement (> or = 100%) at 1 or 3 min without increase at 8 minutes was considered as the primary indicator for malignancy. Twenty carcinomas, one metastatic non-Hodgkin lymphoma, six fibroadenomas, and six other benign findings were histologically assessed. Six cases had negative fine needle aspiration cytology and at least a 2 year negative follow-up.
RESULTS: hCT showed a 100% sensitivity and 83.3% specificity. Considering carcinomas and fibroadenomas, significant differences were found for the percent enhancement at 1 min (p = 0.002) as well as for the density increase or decrease at 3 versus 1 min (p = 0.0035), at 8 versus 1 min (p = 0.0027), and at 8 versus 3 min (p = 0.0180).
CONCLUSION: hCT proved to have a high diagnostic efficacy in evaluating breast tumors. Even though it involves some exposure to radiation, it should be considered in patients in whom MR is contraindicated.
METHOD: Thirty-six patients with 39 suspected lesions underwent breast hCT before and 1, 3, and 8 min after intravenous contrast medium administration. A marked enhancement (> or = 100%) at 1 or 3 min without increase at 8 minutes was considered as the primary indicator for malignancy. Twenty carcinomas, one metastatic non-Hodgkin lymphoma, six fibroadenomas, and six other benign findings were histologically assessed. Six cases had negative fine needle aspiration cytology and at least a 2 year negative follow-up.
RESULTS: hCT showed a 100% sensitivity and 83.3% specificity. Considering carcinomas and fibroadenomas, significant differences were found for the percent enhancement at 1 min (p = 0.002) as well as for the density increase or decrease at 3 versus 1 min (p = 0.0035), at 8 versus 1 min (p = 0.0027), and at 8 versus 3 min (p = 0.0180).
CONCLUSION: hCT proved to have a high diagnostic efficacy in evaluating breast tumors. Even though it involves some exposure to radiation, it should be considered in patients in whom MR is contraindicated.
Предметные рубрики MeSH
AdultAgedBiopsy, NeedleBreast NeoplasmsCarcinoma, Ductal, BreastContraindicationsContrast MediaFemaleFibroadenomaFollow-Up StudiesHumansImage Processing, Computer-AssistedInjections, IntravenousLymphoma, Non-HodgkinMagnetic Resonance ImagingMammographyMiddle AgedNeoplasm InvasivenessRadiographic Image EnhancementSensitivity and SpecificityTime FactorsTomography, X-Ray Computed