Obesity surgery · 2025
Metabolic and Bariatric Surgery and Depression in US Adults: A Cross-Sectional Analysis of NHANES 2015-2018.
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Liu Siqi, Jiao Yan, Wang Chunxi
Аннотация
BACKGROUND: The relationship between Metabolic and bariatric surgery (MBS) and depression remains unclear, with some studies suggesting mental health improvements while others report persistent or worsening symptoms.
OBJECTIVES: This study aims to explore the relationship between MBS (MBS) and depression.
METHODS: Using NHANES 2015-2018 data, we conducted a cross-sectional analysis of 7,678 adults to examine the association between MBS and depression (measured by PHQ-9 scores). Multivariable linear regression models adjusted for demographic, lifestyle, and health-related confounders.
RESULTS: Individuals with a history of MBS had higher unadjusted depression scores compared to those without surgery. However, after full adjustment for confounding factors, the association was no longer statistically significant (β = 1.03, p = 0.06). Subgroup analyses suggested that low-income individuals who had undergone MBS had significantly higher depression scores compared to their non-surgery counterparts (β = 4.19, p = 0.002), while no significant differences were observed in other subgroups.
CONCLUSIONS: MBS was not independently associated with depression in the general population after adjustment for confounders. However, socioeconomic factors may influence post-surgical mental health outcomes, highlighting the need for targeted psychological support.
OBJECTIVES: This study aims to explore the relationship between MBS (MBS) and depression.
METHODS: Using NHANES 2015-2018 data, we conducted a cross-sectional analysis of 7,678 adults to examine the association between MBS and depression (measured by PHQ-9 scores). Multivariable linear regression models adjusted for demographic, lifestyle, and health-related confounders.
RESULTS: Individuals with a history of MBS had higher unadjusted depression scores compared to those without surgery. However, after full adjustment for confounding factors, the association was no longer statistically significant (β = 1.03, p = 0.06). Subgroup analyses suggested that low-income individuals who had undergone MBS had significantly higher depression scores compared to their non-surgery counterparts (β = 4.19, p = 0.002), while no significant differences were observed in other subgroups.
CONCLUSIONS: MBS was not independently associated with depression in the general population after adjustment for confounders. However, socioeconomic factors may influence post-surgical mental health outcomes, highlighting the need for targeted psychological support.