Transplantation proceedings · 2025
Enhancing Organ Donation from Brain-Dead Patients: Efficacy of an Innovative Physician-Patient Communication Model.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Zhang Min, Zhou Gaosheng
Аннотация
OBJECTIVE: To identify factors influencing organ donation success among brain-dead patients and evaluate the efficacy of a novel physician-patient communication model ("1T+3S Principles" and "T-F-B Framework").
METHODS: In this randomized controlled trial, 153 eligible brain-dead patients from a tertiary ICU (September 2020-December 2023) were allocated to a control group (conventional communication, n = 77) or study group (innovative model, n = 76). Donation success rates, organ utilization, and predictive factors were analyzed.
RESULTS: The study group demonstrated significantly higher donation success rates (heart: 27.63% vs. 3.90%; liver: 26.32% vs. 3.90%; kidney: 25.00% vs. 3.90%; all P < .001) and organ utilization (P < .05). Key success predictors included: higher education (Master's↑: OR = 5.65, P = .010), hospitalization >7 days (OR = 7.70, P < .001), fewer immediate family members (OR = 6.58, P < .001), and reduced extended family intervention (OR = 7.16, P < .001). Low-income families (Monthly income<3000 RMB) showed greater donation acceptance (P = .003).
CONCLUSION: The innovative communication model significantly improves donation success, particularly among educated, low-income families with streamlined decision-makers. Systematic adoption of this framework could mitigate China's organ shortage crisis.
METHODS: In this randomized controlled trial, 153 eligible brain-dead patients from a tertiary ICU (September 2020-December 2023) were allocated to a control group (conventional communication, n = 77) or study group (innovative model, n = 76). Donation success rates, organ utilization, and predictive factors were analyzed.
RESULTS: The study group demonstrated significantly higher donation success rates (heart: 27.63% vs. 3.90%; liver: 26.32% vs. 3.90%; kidney: 25.00% vs. 3.90%; all P < .001) and organ utilization (P < .05). Key success predictors included: higher education (Master's↑: OR = 5.65, P = .010), hospitalization >7 days (OR = 7.70, P < .001), fewer immediate family members (OR = 6.58, P < .001), and reduced extended family intervention (OR = 7.16, P < .001). Low-income families (Monthly income<3000 RMB) showed greater donation acceptance (P = .003).
CONCLUSION: The innovative communication model significantly improves donation success, particularly among educated, low-income families with streamlined decision-makers. Systematic adoption of this framework could mitigate China's organ shortage crisis.