Blood · 2024
Coagulation factor XI regulates endothelial cell permeability and barrier function in vitro and in vivo.
СтатьяПоддержка NIH: внешняя программаНазвание и аннотация: Перевод пока не подготовлен
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Puy Cristina, Moellmer Samantha A, Pang Jiaqing, Vu Helen H, Melrose Alexander R, Lorentz Christina U, Tucker Erik I, Shatzel Joseph J, Keshari Ravi S, Lupu Florea, Gailani David, McCarty Owen J T
Аннотация
BACKGROUND: Delayed childbearing has become an increasingly prevalent trend, influenced by various psychological and social factors. This study aimed to explore the impact of these factors on the timing of childbirth among women of reproductive age.
METHODS: A cross-sectional study was conducted with 1,128 women attending their first prenatal visit at six hospitals between January and December 2023. Sociodemographic, psychological, and health-related data were collected through structured interviews and self-administered questionnaires. Bivariate and multivariate analyses were performed to identify significant predictors of delayed childbearing.
RESULTS: Reproductive health issues, educational level, employment status, career advancement aspirations, and age-related anxiety were significantly associated with delayed childbearing. Multivariate logistic regression revealed that reproductive health issues (OR = 2.70), educational level (OR = 1.84), and career aspirations (OR = 2.53) were independent predictors of delayed childbearing. Interestingly, age-related anxiety was associated with an increased likelihood of earlier reproductive decision-making, reducing the odds of delayed childbirth by 69% (OR = 0.31, 95% CI: 0.23-0.56, p < 0.001). Subgroup analysis indicated that both low-income and high-income women were more likely to delay childbirth compared to women with medium income (p < 0.05).
CONCLUSION: Psychological and social factors, including career goals, educational attainment, and reproductive health issues, play a critical role in the decision to delay childbearing. Understanding these influences is essential for developing policies and interventions that support women in making informed reproductive choices. Further research with more diverse populations is needed to confirm these findings and explore the broader societal implications.
METHODS: A cross-sectional study was conducted with 1,128 women attending their first prenatal visit at six hospitals between January and December 2023. Sociodemographic, psychological, and health-related data were collected through structured interviews and self-administered questionnaires. Bivariate and multivariate analyses were performed to identify significant predictors of delayed childbearing.
RESULTS: Reproductive health issues, educational level, employment status, career advancement aspirations, and age-related anxiety were significantly associated with delayed childbearing. Multivariate logistic regression revealed that reproductive health issues (OR = 2.70), educational level (OR = 1.84), and career aspirations (OR = 2.53) were independent predictors of delayed childbearing. Interestingly, age-related anxiety was associated with an increased likelihood of earlier reproductive decision-making, reducing the odds of delayed childbirth by 69% (OR = 0.31, 95% CI: 0.23-0.56, p < 0.001). Subgroup analysis indicated that both low-income and high-income women were more likely to delay childbirth compared to women with medium income (p < 0.05).
CONCLUSION: Psychological and social factors, including career goals, educational attainment, and reproductive health issues, play a critical role in the decision to delay childbearing. Understanding these influences is essential for developing policies and interventions that support women in making informed reproductive choices. Further research with more diverse populations is needed to confirm these findings and explore the broader societal implications.