Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2025
Incidence and Associated Factors for Post-Transplant Diabetes Mellitus (PTDM) After Kidney Transplant in PMK-KT Center: Single Center.
СтатьяНазвание и аннотация: Перевод в очереди
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Inkong Pitchamon, Duenchai Nitichai, Nata Naowanit, Tangwonglert Theerasak, Chaiprasert Amnart, Satirapoj Bancha, Ruangkanchanasetr Prajej, Kaewput Wisit
Аннотация
BACKGROUND: Post-transplant diabetes mellitus (PTDM) presents a growing global health challenge. Limited understanding of PTDM in Asians needs to be explored.
OBJECTIVES: This study aims to identify the cumulative incidence of PTDM and the associated risk factors in kidney transplant recipients.
METHODS: This retrospective cohort was performed at the Kidney Transplant Center of Phramongkutklao Hospital (PMK-KT), Thailand, from January 1989 to January 2022. Demographic information, comorbid disorders, laboratory test results, pharmacological treatments, and drug concentrations were recorded. Utilizing multiple logistic regression analysis, we assessed the risk of PTDM.
RESULTS: The total of 174 KT recipients was eligible for analysis. The cumulative incidence of PTDM was 16.7% (95% CI: 11.46%-23.05%). Multivariable logistic regression identified chronic hepatitis C, Everolimus usage, graft rejection, and post-transplant hypomagnesemia as predictors of PTDM. The overall mortality was 20.5% (95% CI: 14.62%-27.43%).
CONCLUSION: A slightly increased cumulative incidence of PTDM was observed. Several risk factors were identified.
OBJECTIVES: This study aims to identify the cumulative incidence of PTDM and the associated risk factors in kidney transplant recipients.
METHODS: This retrospective cohort was performed at the Kidney Transplant Center of Phramongkutklao Hospital (PMK-KT), Thailand, from January 1989 to January 2022. Demographic information, comorbid disorders, laboratory test results, pharmacological treatments, and drug concentrations were recorded. Utilizing multiple logistic regression analysis, we assessed the risk of PTDM.
RESULTS: The total of 174 KT recipients was eligible for analysis. The cumulative incidence of PTDM was 16.7% (95% CI: 11.46%-23.05%). Multivariable logistic regression identified chronic hepatitis C, Everolimus usage, graft rejection, and post-transplant hypomagnesemia as predictors of PTDM. The overall mortality was 20.5% (95% CI: 14.62%-27.43%).
CONCLUSION: A slightly increased cumulative incidence of PTDM was observed. Several risk factors were identified.