Contemporary oncology (Poznan, Poland) · 2014
Recovery from paraplegia with administration of erlotinib in a patient with lung adenocarcinoma.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Alibaz-Öner Fatma, Kaymaz-Tahra Sema, Ince Burak, Bölek Ertugrul Çağrı, Yüce Inel Tuba, Öz Hande Ece, Şak Tuncer, Özdede Ayşe, Toker Dinçer Zeynep, Yıldırım Fatih, Kenar Gokce, Turten-Kaymaz Tugce, Alpay-Kanitez Nilufer, Bes Cemal, Karadağ Omer, Hatemi Gulen, Akar Servet, Onen Fatos, Seyahi Emire, Aksu Kenan, Keser Gökhan, Gul Ahmet, Direskeneli Haner
Аннотация
OBJECTIVES: To develop evidence-based and expert opinion guided recommendations for Takayasu's arteritis (TAK) management.
METHODS: A systematic literature review was conducted following the principles outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. To structure the key clinical questions, the task force employed the Population, Intervention, Comparison, and Outcome (PICO) format. The European League Against Rheumatism (EULAR) standardised operating procedures was subsequently applied to grade the quality of the collected evidence and determine the strength of each recommendation.
RESULTS: This guideline provides 40 recommendations under the headings: diagnosis, follow-up, medical treatment, pregnancy and surgical interventions. As randomised controlled trials are very limited in number without conclusive results, most data come from case series with low-level evidence. We recommend conventional immunosuppressives as the first choice during remission-induction. Tumour necrosis factor-inhibitors or tocilizumab can be considered in patients with relapsing or refractory disease despite conventional immunosuppressives.
CONCLUSIONS: The first Turkish Takayasu Arteritis Study Group recommendations deriving from a current literature review and large clinical experience, aim to guide clinicians not only in Turkey, but also in other countries who are providing health care to patients with TAK.
METHODS: A systematic literature review was conducted following the principles outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. To structure the key clinical questions, the task force employed the Population, Intervention, Comparison, and Outcome (PICO) format. The European League Against Rheumatism (EULAR) standardised operating procedures was subsequently applied to grade the quality of the collected evidence and determine the strength of each recommendation.
RESULTS: This guideline provides 40 recommendations under the headings: diagnosis, follow-up, medical treatment, pregnancy and surgical interventions. As randomised controlled trials are very limited in number without conclusive results, most data come from case series with low-level evidence. We recommend conventional immunosuppressives as the first choice during remission-induction. Tumour necrosis factor-inhibitors or tocilizumab can be considered in patients with relapsing or refractory disease despite conventional immunosuppressives.
CONCLUSIONS: The first Turkish Takayasu Arteritis Study Group recommendations deriving from a current literature review and large clinical experience, aim to guide clinicians not only in Turkey, but also in other countries who are providing health care to patients with TAK.